Welcome to the Multi Locus Sequence Typing home page

MLST is a nucleotide sequence based approach for the unambiguous characterisation of isolates of bacteria and other organisms via the internet.

The aim of MLST is to provide a portable, accurate, and highly discriminating typing system that can be used for most bacteria and some other organisms. It is envisaged that this approach will be particularly helpful for the typing of bacterial pathogens.

To achieve this aim we have taken the proven concepts of multilocus enzyme electrophoresis (MLEE) and have adapted them so that alleles at each locus are defined directly, by nucleotide sequencing, rather than indirectly from the electrophoretic moblity of their gene products.

MLST was developed in the laboratories of Martin Maiden, Dominique Caugant, Ian Feavers, Mark Achtman and Brian Spratt.

This site is hosted at Imperial College with funding from the Wellcome Trust.
The location of the subsites for the individual species are shown on their respective front pages.

For general information please Click here or to register feedback or interest Click here

News

C. trachomatis MLST scheme now available
Click here to visit the site

Leptospira spp MLST scheme launched
Click here to visit the site

Borrelia burgdorferi MLST scheme launched
Click here to visit the site

MLST-maps : a facility for mapping the global distribution of Sequence Types. The MLST databases have been made available to view using either Google Maps or Google Earth. Click here to visit the site